We conducted a case-cohort analysis in the Northern Manhattan Study, a prospective cohort study of stroke risk factors. If true, we would expect an association with cryptogenic or cardioembolic stroke rather than noncardioembolic stroke. 2 From the Department of Neurology, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York Department of Neurology (M.H., Y.P.M., S.Y., K.C., M.S.V.E.) and Division of Cardiology (M.R.D.T.), Columbia College of Physicians and Surgeons, New York Department of Biostatistics, Columbia Mailman School of Public Health, New York (K.C.) Department of Neurology, Human Genetics, and Public Health Sciences, Miller School of Medicine, University of Miami, FL (R.L.S.) Departments of Epidemiology and Prevention (E.Z.S.) and Internal Medicine-Cardiology (E.Z.S.), Epidemiological Cardiology Research Center, Wake Forest School of Medicine, Winston-Salem, NC and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York (M.S.V.E.).Įlectrocardiographic left atrial abnormality has been associated with stroke independently of atrial fibrillation (AF), suggesting that atrial thromboembolism may occur in the absence of AF. 1 From the Department of Neurology, Feil Family Brain and Mind Research Institute (H.K.) and Division of Cardiology (P.M.O.), Weill Cornell Medical College, New York Department of Neurology (M.H., Y.P.M., S.Y., K.C., M.S.V.E.) and Division of Cardiology (M.R.D.T.), Columbia College of Physicians and Surgeons, New York Department of Biostatistics, Columbia Mailman School of Public Health, New York (K.C.) Department of Neurology, Human Genetics, and Public Health Sciences, Miller School of Medicine, University of Miami, FL (R.L.S.) Departments of Epidemiology and Prevention (E.Z.S.) and Internal Medicine-Cardiology (E.Z.S.), Epidemiological Cardiology Research Center, Wake Forest School of Medicine, Winston-Salem, NC and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York (M.S.V.E.).
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